ASTM-E1147:2005 Edition

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E1147-92(2005) Standard Test Method for Partition Coefficient (N-Octanol/Water) Estimation by Liquid Chromatography

Published By	Publication Date	Number of Pages
ASTM	2005	4

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Categories: 71.080.60 - Alcohols. Ethers, ASTM

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Description

ASTM E1147-92-Reapproved2005

Withdrawn Standard: Standard Test Method for Partition Coefficient (N-Octanol/Water) Estimation by Liquid Chromatography (Withdrawn 2013)

ASTM E1147

Scope

1.1 This test method describes a procedure for the estimation of the log of the octanol/water partition coefficient (log Kow) of chemicals over the range from 0 to 8.

1.2 This test method uses an empirically derived equation to relate the octanol/water partition coefficient to an experimentally determined retention time on a liquid chromatographic column.

1.3 This test method has been designed to estimate log Kow values for both non-ionizable and ionizable compounds. This is accomplished by buffering the liquid chromatographic solvent at a pH that will force the test compound into either the non-ionized or ionized form.

1.4 This test method requires some knowledge of the detector response to the chemical being tested.

1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish safety and health practices and determine the applicability of regulatory limitations prior to use.

Keywords

ICS Code

ICS Number Code 71.080.60 (Alcohols. Ethers)

DOI: 10.1520/E1147-92R05

PDF Catalog

PDF Pages	PDF Title
1	Scope Referenced Documents Terminology Summary of Test Method
2	Significance and Use Apparatus Reagents and Materials
3	Sampling Calibration Procedure Calculation of Results Report Precision and Bias
4	REFERENCES

Additional information

Standard Title	E1147-92(2005) Standard Test Method for Partition Coefficient (N-Octanol/Water) Estimation by Liquid Chromatography
Published Code	ASTM
Publication Date	2005
Pages Count	4
ICS Codes	71.080.60 - Alcohols. Ethers